Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance

The transcription factor AP-1 is downstream of growth factor (GF) receptors (GFRs) and stress-related kinases, both of which are implicated in breast cancer endocrine-resistance. Previously, we have suggested that acquired endocrine-resistance is associated with increased activity of AP-1 in an in v...

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Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Malorni, Luca, Giuliano, Mario, Migliaccio, Ilenia, Wang, Tao, Creighton, Chad J., Lupien, Mathieu, Fu, Xiaoyong, Hilsenbeck, Susan G., Healy, Nuala, De Angelis, Carmine, Mazumdar, Abhijit, Trivedi, Meghana V., Massarweh, Suleiman, Gutierrez, Carolina, De Placido, Sabino, Jeselsohn, Rinath, Brown, Myles, Brown, Powel H., Osborne, C. Kent, Schiff, Rachel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867274/
https://ncbi.nlm.nih.gov/pubmed/26965145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0423
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