ETHANOL INHIBITS METHIONINE ADENOSYLTRANSFERASE II (MAT II) ACTIVITY AND S-ADENOSYLMETHIONINE (SAMe) BIOSYNTHESIS AND ENHANCES CASPASE-3 DEPENDENT CELL DEATH IN T LYMHOCYTES: RELEVANCE TO ALCOHOL INDUCED IMMUNOSUPPRESSION

An important aspect in alcohol abuse associated immune suppression is the loss of T helper CD4(+) lymphocytes leading to an impairment of multiple immune functions. Our work has shown that ethanol can sensitize CD4(+) T lymphocytes to activation-induced, caspase-3 dependent cell death (AICD). It has...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Nutr Biochem
Egile Nagusiak: Hote, Prachi T., Sahoo, Rashmita, Jani, Tanvi S., Ghare, Smita S., Chen, Theresa, Joshi-Barve, Swati, McClain, Craig J., Barve, Shirish S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867115/
https://ncbi.nlm.nih.gov/pubmed/17869084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2007.05.010
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