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ETHANOL INHIBITS METHIONINE ADENOSYLTRANSFERASE II (MAT II) ACTIVITY AND S-ADENOSYLMETHIONINE (SAMe) BIOSYNTHESIS AND ENHANCES CASPASE-3 DEPENDENT CELL DEATH IN T LYMHOCYTES: RELEVANCE TO ALCOHOL INDUCED IMMUNOSUPPRESSION
An important aspect in alcohol abuse associated immune suppression is the loss of T helper CD4(+) lymphocytes leading to an impairment of multiple immune functions. Our work has shown that ethanol can sensitize CD4(+) T lymphocytes to activation-induced, caspase-3 dependent cell death (AICD). It has...
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| Publicado no: | J Nutr Biochem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867115/ https://ncbi.nlm.nih.gov/pubmed/17869084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2007.05.010 |
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