Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations

Lignende værker

• Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity
  af: Shah, Manish B., et al.
  Udgivet: (2017)
• Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed Upon Binding Multiple Amlodipine Molecules()
  af: Shah, Manish B., et al.
  Udgivet: (2012)
• Functional Importance of a Peripheral Pocket in Mammalian Cytochrome P450 2B Enzymes()
  af: Jang, Hyun-Hee, et al.
  Udgivet: (2015)
• Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison
  af: Shah, Manish B., et al.
  Udgivet: (2015)
• Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism
  af: Shah, Manish B., et al.
  Udgivet: (2016)