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N-Acetyl Cysteine does not prevent liver toxicity from chronic low dose plus sub-acute high dose paracetamol exposure in young or old mice

Paracetamol is an analgesic commonly used by people of all ages, which is well documented to cause severe hepatotoxicity with acute over-exposures. The risk of hepatotoxicity from non-acute paracetamol exposures is less extensively studied, and this is the exposure most common in older adults. Evide...

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Dades bibliogràfiques
Publicat a:Fundam Clin Pharmacol
Autors principals: Kane, Alice-Elizabeth, Huizer-Pajkos, Aniko, Mach, John, McKenzie, Catriona, Mitchell, Sarah-Jayne, de Cabo, Rafael, Jones, Brett, Cogger, Victoria, Le Couteur, David G, Hilmer, Sarah-Nicole
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864111/
https://ncbi.nlm.nih.gov/pubmed/26821200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/fcp.12184
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