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The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats

Apoptosis is increased in the liver in old age and is a common pathological feature of liver disease. The mitochondria play a key role in regulating apoptosis via the intrinsic death pathway. As the effect of aging on this pathway is unclear, we aimed to characterize the impact of aging on the hepat...

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Publicado en:Exp Gerontol
Main Authors: Mach, John, Huizer-Pajkos, Aniko, Kane, Alice, Jones, Brett, McKenzie, Catriona, Mitchell, Sarah J., de Cabo, Rafael, Cogger, Victoria C., Le Couteur, David G., Hilmer, Sarah N.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854160/
https://ncbi.nlm.nih.gov/pubmed/25910621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.04.009
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