Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type

Acetaminophen is a commonly used analgesic that can cause severe hepatotoxicity in overdose. Despite old age and frailty being associated with extensive and long-term utilization of acetaminophen and a high prevalence of adverse drug reactions, there is limited information on the risks of toxicity f...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Kane, Alice E., Mitchell, Sarah J., Mach, John, Huizer-Pajkos, Aniko, McKenzie, Catriona, Jones, Brett, Cogger, Victoria, Le Couteur, David G., de Cabo, Rafael, Hilmer, Sarah N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976491/
https://ncbi.nlm.nih.gov/pubmed/26615879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.11.013
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