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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...

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Publicat a:Genes Dev
Autors principals: Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863743/
https://ncbi.nlm.nih.gov/pubmed/27151974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278424.116
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