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Modeling SF3B1 Mutations in Cancer: Advances, Challenges, and Opportunities
In this issue of Cancer Cell, Obeng et al. identify the consequences of expressing the most common mutation in the spliceosomal gene SF3B1 on hematopoiesis. The knockin mouse model described represents a valuable tool to dissect the effects of SF3B1 mutations on transformation, splicing, and less we...
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| Udgivet i: | Cancer Cell |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5569387/ https://ncbi.nlm.nih.gov/pubmed/27622329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.08.013 |
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