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The biological function and clinical significance of SF3B1 mutations in cancer

Spliceosome mutations have become the most interesting mutations detected in human cancer in recent years. The spliceosome, a large, dynamic multimegadalton small nuclear ribonucleoprotein composed of small nuclear RNAs associated with proteins, is responsible for removing introns from precursor mRN...

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Podrobná bibliografie
Vydáno v:Biomark Res
Hlavní autoři: Zhou, Zhixia, Gong, Qi, Wang, Yin, Li, Mengkun, Wang, Lu, Ding, Hongfei, Li, Peifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469106/
https://ncbi.nlm.nih.gov/pubmed/32905346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-00220-5
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