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Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms
Precursor mRNA splicing is catalyzed by the spliceosome, a macromolecule composed of small nuclear RNAs associated with proteins. The SF3B1 gene encodes subunit 1 of the splicing factor 3b, which is important for anchoring the spliceosome to precursor mRNA. In 2011, whole-exome sequencing studies sh...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790951/ https://ncbi.nlm.nih.gov/pubmed/23160465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-399725 |
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