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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863743/
https://ncbi.nlm.nih.gov/pubmed/27151974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278424.116
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