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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...

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Foilsithe in:Genes Dev
Main Authors: Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863743/
https://ncbi.nlm.nih.gov/pubmed/27151974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278424.116
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