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Network of remote and local protein dynamics in dihydrofolate reductase catalysis
Molecular dynamics calculations and bionformatic studies of dihydrofolate reductase (DHFR) have suggested a network of coupled motions across the whole protein that is correlated to the reaction coordinate. Experimental studies demonstrated that distal residues G121, M42 and F125 in E. coli DHFR par...
Gorde:
| Argitaratua izan da: | ACS Catal |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863459/ https://ncbi.nlm.nih.gov/pubmed/27182453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b00331 |
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