Učitavanje...
Network of remote and local protein dynamics in dihydrofolate reductase catalysis
Molecular dynamics calculations and bionformatic studies of dihydrofolate reductase (DHFR) have suggested a network of coupled motions across the whole protein that is correlated to the reaction coordinate. Experimental studies demonstrated that distal residues G121, M42 and F125 in E. coli DHFR par...
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| Izdano u: | ACS Catal |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863459/ https://ncbi.nlm.nih.gov/pubmed/27182453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b00331 |
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