Загрузка...

Dihydrofolate reductase as a model for studies of enzyme dynamics and catalysis

Dihydrofolate reductase from Escherichia coli (ecDHFR) serves as a model system for investigating the role of protein dynamics in enzyme catalysis. We discuss calculations predicting a network of dynamic motions that is coupled to the chemical step catalyzed by this enzyme. Kinetic studies testing t...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :F1000Res
Главный автор: Kohen, Amnon
Формат: Artigo
Язык:Inglês
Опубликовано: F1000Research 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754028/
https://ncbi.nlm.nih.gov/pubmed/26918149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.6968.1
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!