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The therapeutic potential of RORγ modulators in the treatment of human disease

Nuclear receptors (NR) are ligand-regulated transcription factors that bind DNA in proximity to their target genes and exert their effects as a result of binding by small molecule ligands such as sterols, lipids, fatty acids, retinoids, and steroid hormones. The retinoic acid receptor-related orphan...

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Détails bibliographiques
Publié dans:J Exp Pharmacol
Auteurs principaux: Chang, Mi Ra, Goswami, Devrishi, Mercer, Becky A, Griffin, Patrick R
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863310/
https://ncbi.nlm.nih.gov/pubmed/27186126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JEP.S27078
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