1,25-dihydroxyvitamin D alone improves Skeletal Growth, Microarchitecture and Strength in a Murine model of XLH, despite enhanced FGF23 expression

X-linked hypophosphatemia (XLH) is characterized by impaired renal tubular reabsorption of phosphate due to increased circulating FGF23 levels, resulting in rickets in growing children and impaired bone mineralization. Increased FGF23 decreases renal brush border membrane sodium-dependent phosphate...

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Publicat a:J Bone Miner Res
Autors principals: Liu, Eva S., Martins, Janaina S., Raimann, Adalbert, Chae, Byongsoo Timothy, Brooks, Daniel J., Jorgetti, Vanda, Bouxsein, Mary L., Demay, Marie B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862933/
https://ncbi.nlm.nih.gov/pubmed/26751835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2783
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