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1,25-dihydroxyvitamin D alone improves Skeletal Growth, Microarchitecture and Strength in a Murine model of XLH, despite enhanced FGF23 expression

X-linked hypophosphatemia (XLH) is characterized by impaired renal tubular reabsorption of phosphate due to increased circulating FGF23 levels, resulting in rickets in growing children and impaired bone mineralization. Increased FGF23 decreases renal brush border membrane sodium-dependent phosphate...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Liu, Eva S., Martins, Janaina S., Raimann, Adalbert, Chae, Byongsoo Timothy, Brooks, Daniel J., Jorgetti, Vanda, Bouxsein, Mary L., Demay, Marie B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862933/
https://ncbi.nlm.nih.gov/pubmed/26751835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2783
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