Impaired 1,25 dihydroxyvitamin D(3) action and hypophosphatemia underlie the altered lacuno-canalicular remodeling observed in the Hyp mouse model of XLH

Osteocytes remodel the perilacunar matrix and canaliculi. X-linked hypophosphatemia (XLH) is characterized by elevated serum levels of fibroblast growth factor 23 (FGF23), leading to decreased 1,25 dihydroxyvitamin D(3) (1,25D) production and hypophosphatemia. Bones from mice with XLH (Hyp) have enl...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Yuan, Ye, Jagga, Supriya, Martins, Janaina S., Rana, Rakshya, Pajevic, Paola Divieti, Liu, Eva S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158930/
https://ncbi.nlm.nih.gov/pubmed/34043707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252348
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