Impaired 1,25 dihydroxyvitamin D(3) action and hypophosphatemia underlie the altered lacuno-canalicular remodeling observed in the Hyp mouse model of XLH

Osteocytes remodel the perilacunar matrix and canaliculi. X-linked hypophosphatemia (XLH) is characterized by elevated serum levels of fibroblast growth factor 23 (FGF23), leading to decreased 1,25 dihydroxyvitamin D(3) (1,25D) production and hypophosphatemia. Bones from mice with XLH (Hyp) have enl...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Yuan, Ye, Jagga, Supriya, Martins, Janaina S., Rana, Rakshya, Pajevic, Paola Divieti, Liu, Eva S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158930/
https://ncbi.nlm.nih.gov/pubmed/34043707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252348
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