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Ikaros Is a Negative Regulator of B1 Cell Development and Function
B1 B cells secrete most of the circulating natural antibodies and are considered key effector cells of the innate immune response. However, B1 cell-associated antibodies often cross-react with self-antigens, which leads to autoimmunity, and B1 cells have been implicated in cancer. How B1 cell activi...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861476/ https://ncbi.nlm.nih.gov/pubmed/26841869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704239 |
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