Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

BACKGROUND. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers of response. Human equilibrative nucleoside transporter 1 (hENT-1) is the major transporter involved in gemcitabine intracellular uptake. This...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Brandi, Giovanni, Deserti, Marzia, Vasuri, Francesco, Farioli, Andrea, Degiovanni, Alessio, Palloni, Andrea, Frega, Giorgio, Barbera, Maria A., de Lorenzo, Stefania, Garajova, Ingrid, Di Marco, Mariacristina, Pinna, Antonio D., Cescon, Matteo, Cucchetti, Alessandro, Ercolani, Giorgio, D’Errico-Grigioni, Antonietta, Pantaleo, Maria A., Biasco, Guido, Tavolari, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Hepatobiliary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861359/
https://ncbi.nlm.nih.gov/pubmed/27032872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0356
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