Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

BACKGROUND. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers of response. Human equilibrative nucleoside transporter 1 (hENT-1) is the major transporter involved in gemcitabine intracellular uptake. This...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncologist
Auteurs principaux: Brandi, Giovanni, Deserti, Marzia, Vasuri, Francesco, Farioli, Andrea, Degiovanni, Alessio, Palloni, Andrea, Frega, Giorgio, Barbera, Maria A., de Lorenzo, Stefania, Garajova, Ingrid, Di Marco, Mariacristina, Pinna, Antonio D., Cescon, Matteo, Cucchetti, Alessandro, Ercolani, Giorgio, D’Errico-Grigioni, Antonietta, Pantaleo, Maria A., Biasco, Guido, Tavolari, Simona
Format: Artigo
Langue:Inglês
Publié: AlphaMed Press 2016
Sujets:
Hepatobiliary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861359/
https://ncbi.nlm.nih.gov/pubmed/27032872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0356
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