Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

BACKGROUND. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers of response. Human equilibrative nucleoside transporter 1 (hENT-1) is the major transporter involved in gemcitabine intracellular uptake. This...

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Foilsithe in:Oncologist
Main Authors: Brandi, Giovanni, Deserti, Marzia, Vasuri, Francesco, Farioli, Andrea, Degiovanni, Alessio, Palloni, Andrea, Frega, Giorgio, Barbera, Maria A., de Lorenzo, Stefania, Garajova, Ingrid, Di Marco, Mariacristina, Pinna, Antonio D., Cescon, Matteo, Cucchetti, Alessandro, Ercolani, Giorgio, D’Errico-Grigioni, Antonietta, Pantaleo, Maria A., Biasco, Guido, Tavolari, Simona
Formáid: Artigo
Teanga:Inglês
Foilsithe: AlphaMed Press 2016
Ábhair:
Hepatobiliary
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861359/
https://ncbi.nlm.nih.gov/pubmed/27032872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0356
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