Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

BACKGROUND. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers of response. Human equilibrative nucleoside transporter 1 (hENT-1) is the major transporter involved in gemcitabine intracellular uptake. This...

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Detalles Bibliográficos
Publicado en:Oncologist
Main Authors: Brandi, Giovanni, Deserti, Marzia, Vasuri, Francesco, Farioli, Andrea, Degiovanni, Alessio, Palloni, Andrea, Frega, Giorgio, Barbera, Maria A., de Lorenzo, Stefania, Garajova, Ingrid, Di Marco, Mariacristina, Pinna, Antonio D., Cescon, Matteo, Cucchetti, Alessandro, Ercolani, Giorgio, D’Errico-Grigioni, Antonietta, Pantaleo, Maria A., Biasco, Guido, Tavolari, Simona
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2016
Assuntos:
Hepatobiliary
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861359/
https://ncbi.nlm.nih.gov/pubmed/27032872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0356
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