Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

BACKGROUND. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers of response. Human equilibrative nucleoside transporter 1 (hENT-1) is the major transporter involved in gemcitabine intracellular uptake. This...

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Bibliografski detalji
Izdano u:Oncologist
Glavni autori: Brandi, Giovanni, Deserti, Marzia, Vasuri, Francesco, Farioli, Andrea, Degiovanni, Alessio, Palloni, Andrea, Frega, Giorgio, Barbera, Maria A., de Lorenzo, Stefania, Garajova, Ingrid, Di Marco, Mariacristina, Pinna, Antonio D., Cescon, Matteo, Cucchetti, Alessandro, Ercolani, Giorgio, D’Errico-Grigioni, Antonietta, Pantaleo, Maria A., Biasco, Guido, Tavolari, Simona
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2016
Teme:
Hepatobiliary
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861359/
https://ncbi.nlm.nih.gov/pubmed/27032872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0356
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