טוען...
The Scaffold Protein KSR1, A Novel Therapeutic Target for the Treatment of Merlin-Deficient Tumors
Merlin has broad tumor suppressor functions as its mutations have been identified in multiple benign tumors and malignant cancers. In all schwannomas, the majority of meningiomas and 1/3 of ependymomas Merlin loss is causative. In Neurofibromatosis type 2, a dominantly inherited tumor disease due to...
שמור ב:
| הוצא לאור ב: | Oncogene |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861249/ https://ncbi.nlm.nih.gov/pubmed/26549023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.404 |
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