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The p53/mouse double minute 2 homolog complex deregulation in merlin‐deficient tumours

Deficiency of the tumour suppressor merlin leads to the development of schwannomas, meningiomas and ependymomas occurring spontaneously or as a part of the hereditary disease Neurofibromatosis type 2 (NF2). Merlin loss is also found in a proportion of other cancers like mesothelioma, melanoma, breas...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Ammoun, Sylwia, Schmid, Marei Caroline, Zhou, Lu, Hilton, David A., Barczyk, Magdalena, Hanemann, Clemens Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528691/
https://ncbi.nlm.nih.gov/pubmed/25217104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.08.005
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