Merlin-Deficient Human Tumors Show Loss of Contact Inhibition and Activation of Wnt/β-Catenin Signaling Linked to the PDGFR/Src and Rac/PAK Pathways

Neurofibromatosis type 2 (NF2) is an inherited predisposition cancer syndrome characterized by the development of multiple benign tumors in the nervous system including schwannomas, meningiomas, and ependymomas. Using a disease model comprising primary human schwannoma cells, we previously demonstra...

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Lu, Ercolano, Emanuela, Ammoun, Sylwia, Schmid, M Caroline, Barczyk, Magdalena A, Hanemann, Clemens Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257450/
https://ncbi.nlm.nih.gov/pubmed/22247700
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