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Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1
DNA damage response mediator protein 53BP1 is a key regulator of non-homologous end-joining (NHEJ) repair. 53BP1 protects DNA broken ends from resection by recruiting two downstream factors, RIF1 (RAP1-interacting factor 1) and PTIP (Pax transactivation domain-interacting protein), to double-strande...
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| Publicado en: | Cell Discov |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860855/ https://ncbi.nlm.nih.gov/pubmed/27462418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.19 |
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