Φορτώνει......
Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells
BRCA1 and 53BP1 play decisive roles in the choice of DNA double-strand break repair mechanisms. BRCA1 promotes DNA end resection and homologous recombination (HR) during S/G(2) phases of the cell cycle, while 53BP1 inhibits end resection and facilitates non-homologous end-joining (NHEJ), primarily d...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Landes Bioscience
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903714/ https://ncbi.nlm.nih.gov/pubmed/24091731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26582 |
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