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Airway epithelial DUOX1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses
BACKGROUND: The interleukin (IL)-1 family member IL-33 plays a critical role in type-2 innate immune responses to allergens, and is an important mediator of allergic asthma. The mechanisms by which allergens provoke epithelial IL-33 secretion are still poorly understood. OBJECTIVE: Based on previous...
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| 發表在: | J Allergy Clin Immunol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860024/ https://ncbi.nlm.nih.gov/pubmed/26597162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.10.003 |
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