Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR

Acrolein is a major thiol-reactive component of cigarette smoke (CS) that is thought to contribute to increased asthma incidence associated with smoking. Here, we explored the effects of acute acrolein exposure on innate airway responses to two common airborne allergens, house dust mite and Alternar...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Lung Cell Mol Physiol
Päätekijät: Danyal, Karamatullah, de Jong, Willem, O'Brien, Edmund, Bauer, Robert A., Heppner, David E., Little, Andrew C., Hristova, Milena, Habibovic, Aida, van der Vliet, Albert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2016
Aiheet:
Aritcles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130541/
https://ncbi.nlm.nih.gov/pubmed/27612966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00276.2016
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