Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds

The human immunodeficiency virus (HIV-1) envelope glycoproteins (Env) mediate virus entry through a series of complex conformational changes triggered by binding to the receptors CD4 and CCR5/CXCR4. Broadly neutralizing antibodies that recognize conserved Env epitopes are thought to be an important...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Madani, Navid, Princiotto, Amy M., Easterhoff, David, Bradley, Todd, Luo, Kan, Williams, Wilton B., Liao, Hua-Xin, Moody, M. Anthony, Phad, Ganesh E., Vázquez Bernat, Néstor, Melillo, Bruno, Santra, Sampa, Smith, Amos B., Karlsson Hedestam, Gunilla B., Haynes, Barton, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859707/
https://ncbi.nlm.nih.gov/pubmed/26962221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03211-15
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