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Effect of the BRCA1-SIRT1-EGFR axis on cisplatin sensitivity in ovarian cancer

There is accumulating evidence that breast cancer 1 (BRCA1), sirtuin 1 (SIRT1), and epidermal growth factor receptor (EGFR) help to modulate cisplatin cytotoxicity. The role of dynamic crosstalk among BRCA1, SIRT1, and EGFR in cisplatin sensitivity remains largely unknown. We found that BRCA1, SIRT1...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Li, Da, Wu, Qi-Jun, Bi, Fang-Fang, Chen, Si-Lei, Zhou, Yi-Ming, Zhao, Yue, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859644/
https://ncbi.nlm.nih.gov/pubmed/27186285
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