ROS-Induced SIRT2 Upregulation Contributes to Cisplatin Sensitivity in Ovarian Cancer

Cisplatin resistance remains a significant obstacle for improving the clinical outcome of ovarian cancer patients. Recent studies have demonstrated that cisplatin is an important inducer of intracellullar reactive oxygen species (ROS), triggering cancer cell death. Sirtuin 2 (SIRT2), a member of cla...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Wang, Wenyu, Im, Jihye, Kim, Soochi, Jang, Suin, Han, Youngjin, Yang, Kyung-Min, Kim, Seong-Jin, Dhanasekaran, Danny N., Song, Yong Sang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698236/
https://ncbi.nlm.nih.gov/pubmed/33207824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9111137
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