PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cells

Malignant cells are subjected to high levels of oxidative stress that arise from the increased production of reactive oxygen species (ROS) due to their altered metabolism. They activate antioxidant mechanisms to relieve the oxidative stress, and thereby acquire resistance to chemotherapeutic agents....

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Publicat a:Oncotarget
Autors principals: Kim, Boyun, Jung, Je Won, Jung, Jaeyoung, Han, Youngjin, Suh, Dong Hoon, Kim, Hee Seung, Dhanasekaran, Danny N., Song, Yong Sang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://ncbi.nlm.nih.gov/pubmed/28947972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19140
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