PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cells

Malignant cells are subjected to high levels of oxidative stress that arise from the increased production of reactive oxygen species (ROS) due to their altered metabolism. They activate antioxidant mechanisms to relieve the oxidative stress, and thereby acquire resistance to chemotherapeutic agents....

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Kim, Boyun, Jung, Je Won, Jung, Jaeyoung, Han, Youngjin, Suh, Dong Hoon, Kim, Hee Seung, Dhanasekaran, Danny N., Song, Yong Sang
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://ncbi.nlm.nih.gov/pubmed/28947972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19140
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