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Activation of LXRɑ/β by cholesterol in malignant ascites promotes chemoresistance in ovarian cancer

BACKGROUND: The purpose of this study was to investigate the role of malignant ascites tumor microenvironment in ovarian cancer progression and chemoresistance. METHODS: A total of 45 patients with ovarian cancer and three benign ascites were collected at the time of clinical intervention. Ascites c...

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Pubblicato in:BMC Cancer
Autori principali: Kim, Soochi, Lee, Maria, Dhanasekaran, Danny N., Song, Yong Sang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288854/
https://ncbi.nlm.nih.gov/pubmed/30526541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5152-5
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