PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cells

Malignant cells are subjected to high levels of oxidative stress that arise from the increased production of reactive oxygen species (ROS) due to their altered metabolism. They activate antioxidant mechanisms to relieve the oxidative stress, and thereby acquire resistance to chemotherapeutic agents....

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Vydáno v:Oncotarget
Hlavní autoři: Kim, Boyun, Jung, Je Won, Jung, Jaeyoung, Han, Youngjin, Suh, Dong Hoon, Kim, Hee Seung, Dhanasekaran, Danny N., Song, Yong Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://ncbi.nlm.nih.gov/pubmed/28947972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19140
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