PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cells

Malignant cells are subjected to high levels of oxidative stress that arise from the increased production of reactive oxygen species (ROS) due to their altered metabolism. They activate antioxidant mechanisms to relieve the oxidative stress, and thereby acquire resistance to chemotherapeutic agents....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Boyun, Jung, Je Won, Jung, Jaeyoung, Han, Youngjin, Suh, Dong Hoon, Kim, Hee Seung, Dhanasekaran, Danny N., Song, Yong Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://ncbi.nlm.nih.gov/pubmed/28947972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19140
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