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Effect of the BRCA1-SIRT1-EGFR axis on cisplatin sensitivity in ovarian cancer

There is accumulating evidence that breast cancer 1 (BRCA1), sirtuin 1 (SIRT1), and epidermal growth factor receptor (EGFR) help to modulate cisplatin cytotoxicity. The role of dynamic crosstalk among BRCA1, SIRT1, and EGFR in cisplatin sensitivity remains largely unknown. We found that BRCA1, SIRT1...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Da, Wu, Qi-Jun, Bi, Fang-Fang, Chen, Si-Lei, Zhou, Yi-Ming, Zhao, Yue, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859644/
https://ncbi.nlm.nih.gov/pubmed/27186285
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