Effect of the BRCA1-SIRT1-EGFR axis on cisplatin sensitivity in ovarian cancer

There is accumulating evidence that breast cancer 1 (BRCA1), sirtuin 1 (SIRT1), and epidermal growth factor receptor (EGFR) help to modulate cisplatin cytotoxicity. The role of dynamic crosstalk among BRCA1, SIRT1, and EGFR in cisplatin sensitivity remains largely unknown. We found that BRCA1, SIRT1...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Li, Da, Wu, Qi-Jun, Bi, Fang-Fang, Chen, Si-Lei, Zhou, Yi-Ming, Zhao, Yue, Yang, Qing
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859644/
https://ncbi.nlm.nih.gov/pubmed/27186285
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