Effect of the BRCA1-SIRT1-EGFR axis on cisplatin sensitivity in ovarian cancer

There is accumulating evidence that breast cancer 1 (BRCA1), sirtuin 1 (SIRT1), and epidermal growth factor receptor (EGFR) help to modulate cisplatin cytotoxicity. The role of dynamic crosstalk among BRCA1, SIRT1, and EGFR in cisplatin sensitivity remains largely unknown. We found that BRCA1, SIRT1...

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Dettagli Bibliografici
Pubblicato in:Am J Transl Res
Autori principali: Li, Da, Wu, Qi-Jun, Bi, Fang-Fang, Chen, Si-Lei, Zhou, Yi-Ming, Zhao, Yue, Yang, Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859644/
https://ncbi.nlm.nih.gov/pubmed/27186285
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