Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4

BACKGROUND AND OBJECTIVES: The effect of mammalian target of rapamycin (mTOR) inhibitors has never been tested in patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this academic, prospective, rando...

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Publicat a:Clin J Am Soc Nephrol
Autors principals: Ruggenenti, Piero, Gentile, Giorgio, Perico, Norberto, Perna, Annalisa, Barcella, Luca, Trillini, Matias, Cortinovis, Monica, Ferrer Siles, Claudia Patricia, Reyes Loaeza, Jorge Arturo, Aparicio, Maria Carolina, Fasolini, Giorgio, Gaspari, Flavio, Martinetti, Davide, Carrara, Fabiola, Rubis, Nadia, Prandini, Silvia, Caroli, Anna, Sharma, Kanishka, Antiga, Luca, Remuzzi, Andrea, Remuzzi, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858487/
https://ncbi.nlm.nih.gov/pubmed/26912555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.09900915
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