Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4

BACKGROUND AND OBJECTIVES: The effect of mammalian target of rapamycin (mTOR) inhibitors has never been tested in patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this academic, prospective, rando...

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Bibliografiske detaljer
Udgivet i:Clin J Am Soc Nephrol
Main Authors: Ruggenenti, Piero, Gentile, Giorgio, Perico, Norberto, Perna, Annalisa, Barcella, Luca, Trillini, Matias, Cortinovis, Monica, Ferrer Siles, Claudia Patricia, Reyes Loaeza, Jorge Arturo, Aparicio, Maria Carolina, Fasolini, Giorgio, Gaspari, Flavio, Martinetti, Davide, Carrara, Fabiola, Rubis, Nadia, Prandini, Silvia, Caroli, Anna, Sharma, Kanishka, Antiga, Luca, Remuzzi, Andrea, Remuzzi, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858487/
https://ncbi.nlm.nih.gov/pubmed/26912555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.09900915
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