Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4

BACKGROUND AND OBJECTIVES: The effect of mammalian target of rapamycin (mTOR) inhibitors has never been tested in patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this academic, prospective, rando...

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Publicado en:Clin J Am Soc Nephrol
Autores principales: Ruggenenti, Piero, Gentile, Giorgio, Perico, Norberto, Perna, Annalisa, Barcella, Luca, Trillini, Matias, Cortinovis, Monica, Ferrer Siles, Claudia Patricia, Reyes Loaeza, Jorge Arturo, Aparicio, Maria Carolina, Fasolini, Giorgio, Gaspari, Flavio, Martinetti, Davide, Carrara, Fabiola, Rubis, Nadia, Prandini, Silvia, Caroli, Anna, Sharma, Kanishka, Antiga, Luca, Remuzzi, Andrea, Remuzzi, Giuseppe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858487/
https://ncbi.nlm.nih.gov/pubmed/26912555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.09900915
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