Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease (ALADIN 2): A randomized, double-blind, placebo-controlled, multicenter trial

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetically determined renal disease. In affected patients, renal function may progressively decline up to end-stage renal disease (ESRD), and approximately 10% of those with ESRD are affected by ADPKD. The somatos...

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Published in:PLoS Med
Main Authors: Perico, Norberto, Ruggenenti, Piero, Perna, Annalisa, Caroli, Anna, Trillini, Matias, Sironi, Sandro, Pisani, Antonio, Riccio, Eleonora, Imbriaco, Massimo, Dugo, Mauro, Morana, Giovanni, Granata, Antonio, Figuera, Michele, Gaspari, Flavio, Carrara, Fabiola, Rubis, Nadia, Villa, Alessandro, Gamba, Sara, Prandini, Silvia, Cortinovis, Monica, Remuzzi, Andrea, Remuzzi, Giuseppe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450618/
https://ncbi.nlm.nih.gov/pubmed/30951521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002777
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