Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4

BACKGROUND AND OBJECTIVES: The effect of mammalian target of rapamycin (mTOR) inhibitors has never been tested in patients with autosomal dominant polycystic kidney disease (ADPKD) and severe renal insufficiency. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this academic, prospective, rando...

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Vydáno v:Clin J Am Soc Nephrol
Hlavní autoři: Ruggenenti, Piero, Gentile, Giorgio, Perico, Norberto, Perna, Annalisa, Barcella, Luca, Trillini, Matias, Cortinovis, Monica, Ferrer Siles, Claudia Patricia, Reyes Loaeza, Jorge Arturo, Aparicio, Maria Carolina, Fasolini, Giorgio, Gaspari, Flavio, Martinetti, Davide, Carrara, Fabiola, Rubis, Nadia, Prandini, Silvia, Caroli, Anna, Sharma, Kanishka, Antiga, Luca, Remuzzi, Andrea, Remuzzi, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858487/
https://ncbi.nlm.nih.gov/pubmed/26912555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.09900915
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