Sirolimus Therapy to Halt the Progression of ADPKD

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, c...

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Detaylı Bibliyografya
Asıl Yazarlar: Perico, Norberto, Antiga, Luca, Caroli, Anna, Ruggenenti, Piero, Fasolini, Giorgio, Cafaro, Mariateresa, Ondei, Patrizia, Rubis, Nadia, Diadei, Olimpia, Gherardi, Giulia, Prandini, Silvia, Panozo, Andrea, Bravo, Rodolfo Flores, Carminati, Sergio, De Leon, Felipe Rodriguez, Gaspari, Flavio, Cortinovis, Monica, Motterlini, Nicola, Ene-Iordache, Bogdan, Remuzzi, Andrea, Remuzzi, Giuseppe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2010
Konular:
Clinical Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900967/
https://ncbi.nlm.nih.gov/pubmed/20466742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121302
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