Sirolimus Therapy to Halt the Progression of ADPKD

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, c...

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Detalhes bibliográficos
Main Authors: Perico, Norberto, Antiga, Luca, Caroli, Anna, Ruggenenti, Piero, Fasolini, Giorgio, Cafaro, Mariateresa, Ondei, Patrizia, Rubis, Nadia, Diadei, Olimpia, Gherardi, Giulia, Prandini, Silvia, Panozo, Andrea, Bravo, Rodolfo Flores, Carminati, Sergio, De Leon, Felipe Rodriguez, Gaspari, Flavio, Cortinovis, Monica, Motterlini, Nicola, Ene-Iordache, Bogdan, Remuzzi, Andrea, Remuzzi, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900967/
https://ncbi.nlm.nih.gov/pubmed/20466742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121302
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