Sirolimus Therapy to Halt the Progression of ADPKD

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, c...

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Dades bibliogràfiques
Autors principals: Perico, Norberto, Antiga, Luca, Caroli, Anna, Ruggenenti, Piero, Fasolini, Giorgio, Cafaro, Mariateresa, Ondei, Patrizia, Rubis, Nadia, Diadei, Olimpia, Gherardi, Giulia, Prandini, Silvia, Panozo, Andrea, Bravo, Rodolfo Flores, Carminati, Sergio, De Leon, Felipe Rodriguez, Gaspari, Flavio, Cortinovis, Monica, Motterlini, Nicola, Ene-Iordache, Bogdan, Remuzzi, Andrea, Remuzzi, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2010
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900967/
https://ncbi.nlm.nih.gov/pubmed/20466742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121302
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