Sirolimus Therapy to Halt the Progression of ADPKD

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, c...

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主要な著者: Perico, Norberto, Antiga, Luca, Caroli, Anna, Ruggenenti, Piero, Fasolini, Giorgio, Cafaro, Mariateresa, Ondei, Patrizia, Rubis, Nadia, Diadei, Olimpia, Gherardi, Giulia, Prandini, Silvia, Panozo, Andrea, Bravo, Rodolfo Flores, Carminati, Sergio, De Leon, Felipe Rodriguez, Gaspari, Flavio, Cortinovis, Monica, Motterlini, Nicola, Ene-Iordache, Bogdan, Remuzzi, Andrea, Remuzzi, Giuseppe
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2010
主題:
Clinical Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900967/
https://ncbi.nlm.nih.gov/pubmed/20466742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009121302
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