Lataa...
Design, synthesis, and kinetic analysis of potent protein N-terminal methyltransferase 1 inhibitors()
The protein N-terminal methyltransferase 1 (NTMT1) methylates the α-N-terminal amines of proteins. NTMT1 is upregulated in a variety of cancers and knockdown of NTMT1 results in cell mitotic defects. Therefore, NTMT1 inhibitors could be potential anticancer therapeutics. This study describes the des...
Tallennettuna:
| Julkaisussa: | Org Biomol Chem |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4857722/ https://ncbi.nlm.nih.gov/pubmed/25712161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00120j |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|